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Lahore, Pakistan. Gunmen detonated a car bomb on Wednesday near police and intelligence agency offices in Lahore that collapsed one building and sheared the walls off others, in one of the deadliest attacks in Pakistan this year.

An estimated 30 people were killed and at least 250 wounded.

Interior Minister Rehman Malik said the bombing could be retaliation for the government’s military offensive to rout Taliban militants from the northwestern Swat Valley.

Lahore, Pakistan’s second-largest city, sits near the Indian border and is considered a liberal, cultural capital. Assaults there have heightened fears that militancy in nuclear-armed Pakistan is spreading well beyond the northwest region bordering Afghanistan. Wednesday’s attack was the third major strike in Lahore in recent months.

No one immediately claimed responsibility for the latest bombing. Police said two suspects were detained.

Raja Riaz, a senior minister in the Punjab provincial government, said that about 30 people were killed. Sajjad Bhutta, another senior government official, said that more than 250 people were wounded.

A police building collapsed in the blast, and rescuers rushed to free officers buried in the rubble.

The explosion also sheared the walls off neighboring buildings in a main business district. The ceilings of operating rooms in a nearby hospital also collapsed, injuring 20 people.

Agents from the Inter-Services Intelligence agency were among the dead, a senior official said on condition of anonymity, because he was not authorized to talk to the media.

“The moment the blast happened, everything went dark in front of my eyes,” said Muhammad Ali, one of the witnesses. “The way the blast happened, then gunfire, it looked as if there was a battle going on.”

Sajjad Bhutta, a senior government official in Lahore, said a car carrying several gunmen pulled up on a street between offices of the emergency police and the intelligence agency, Pakistan’s top spy organization.

“As some people came out from that vehicle and started firing at the ISI office, the guards from inside that building returned fire,” he said. As the shooting continued, the car exploded, he added.

Police had little chance to react to the gunshots before the blast.

“All of a sudden we heard a loud sound and the roof collapsed on us,” said Mohammad Rehman, a police official who was wounded and taken to a nearby hospital. “First of all though, we heard the sound of gunfire, then the blast occurred.”

Malik blamed the attack on militants that government forces are fighting in the Swat Valley and the border region, which US officials and other analysts believe Al Qaeda and Taliban militants are using to plan attacks on Western forces in Afghanistan.

“They are anti-state elements, and after being defeated in Swat, they have moved to our big cities,” Malik told the Express news channel.

President Asif Ali Zardari condemned the attack and said in a statement that the government remained committed to rooting out terrorism.

The offensive in Swat is seen as a test of the government’s resolve to combat the spread of militancy, and is strongly backed by Washington and Pakistan’s other Western allies. The army has said that at least 1,100 militants have been killed in the monthlong operation and that Taliban fighters are in retreat.

The military on Wednesday said that troops had cleared militants out of Piochar, a village in a remote part of Swat that is the rear base for Taliban leader Maulana Fazlullah. It predicted that Mingora, the largest town in the valley, would be cleared of militants within three days.

Two other areas, Sultanwas and Mohmand, had also been emptied of militants and were now safe enough for refugees who had fled the fighting to return home.

It was the first time the military has invited some of the more than two million refugees from the region to return to their villages since the fighting began, setting off an exodus that aid officials have warned could turn into a humanitarian disaster.

Associated Press